Symbol Name ID |
Sppl2a
signal peptide peptidase like 2A MGI:1913802 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Mouse Phenotypes | immune system phenotype |
decreased activation-induced B cell apoptosis |
decreased B cell proliferation |
abnormal class switch recombination |
decreased transitional stage T2 B cell number |
decreased transitional stage T3 B cell number |
abnormal transitional stage B cell morphology |
arrested B cell differentiation |
decreased myeloid dendritic cell number |
decreased plasmacytoid dendritic cell number |
decreased mature B cell number |
decreased B-1 B cell number |
decreased B-2 B cell number |
decreased follicular B cell number |
decreased marginal zone B cell number |
decreased B cell number |
decreased T cell number |
abnormal mature B cell morphology |
small spleen |
abnormal B cell physiology |
abnormal immunoglobulin level |
decreased IgA level |
decreased IgG1 level |
decreased IgG2a level |
decreased IgG2b level |
decreased IgG3 level |
decreased IgG level |
decreased IgM level |
decreased Peyer's patch number |
small Peyer's patches |
abnormal humoral immune response |
decreased response to antigen |
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Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||
Sppl2achompB/Sppl2achompB | * | ||||||||||||||||||||||||||||||||
Sppl2am1Anu/Sppl2am1Anu | |||||||||||||||||||||||||||||||||
Sppl2am1Btlr/Sppl2am1Btlr | |||||||||||||||||||||||||||||||||
Sppl2am2Btlr/Sppl2am2Btlr | |||||||||||||||||||||||||||||||||
Sppl2atm1Basc/Sppl2atm1Basc | |||||||||||||||||||||||||||||||||
Sppl2atm1Dgen/Sppl2atm1Dgen |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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